PHARMX high-shear mixers

PHARMX® High-Shear Granulators

Efficient Mixing and Granulation, Optimized for Your Process

PHARMX high-shear granulators are fully customizable bottom-driven mixing systems engineered to provide homogeneous mixing and efficient granulation. Equipped with an in-bowl, bottom-driven mixing impeller and side-mounted chopper, the PHARMX ensures uniform mixing across a range of R&D, pilot, and production size models.

R&D Scale
PX1

R&D or laboratory-scale units provide effective high-shear granulation for small batches.

Pilot Scale
PX25 - PX150

Pilot systems offer a wide range of options for processing larger batches intended for clinical trial or small-scale production.

Production Scale PX250 - PX1250

Production scale systems for granu- lating very large batches (up to 1250 Liters).


Specifications


Unique Features

Hydraulic Drive System

The hydraulic drive system permits full torque down to ¼ RPM, providing plenty of break-out torque at slow speeds for additional mixing after inspection and continuous discharging to wet milling systems.

Operation Up to 90% Full

The bowl geometry has been optimized to permit loading up to 90% full unlike other mixers that max out at 66-75% full. Larger batches can be run in the PHARMX, maximizing your capital investment.

Dome-Shaped Lid

The dome shaped lid permits the material to perform a complete roll over as it moves up the side of the vessel wall. This ensures efficient mixing even when running at larger operating capacities.

Liftable Tool System

After the cleaning phase is complete, the liftable tool system raises the impeller 4-8” to permit inspection or swabbing of the impeller bottom, seal and bowl bottom.

Auto-Cleaning & Seal Purging Systems

The cleaning of the mixer is executed by running a cleaning recipe that flushes/drains the seal purge system and cleans the bowl, tools and discharge. Combined with liftable tool system the cleaning of the mixer is greatly simplified. The multi-stage seal purging system permits operating at low and high seal flows. This helps prevent dusting when loading and allows setting of the flow to match product characteristics.